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Tophi are tiny, chalk-coloured, stone-like deposits of uric acid that obtain under the skin and therefore are most frequently located in pores and skin across the joints and on the outside in the ear.Dos akan dinaikkan secara beransur-ansur sehingga mencapai paras asid urik yang disasarkan, iaitu kurang daripada 6.0 mg/dL. Bagi pesakit dengan masal